国产xxxxx在线观看_无码A片免费视频完整版_亚洲国产美女精品久久久久∴_最近2019年中文字幕免费下载_色欲网天天无码AV日韩

首頁 資訊 財(cái)經(jīng) 公益 彩店 奇聞 速遞 體育 提點(diǎn) 資訊 綜合 企業(yè) 市場

首頁
你現(xiàn)在的位置:

歐盟重新評估雙酚A對公眾健康的風(fēng)險(xiǎn)

2023-04-20 10:19:39    來源:食品伙伴網(wǎng)    作者:


(資料圖片僅供參考)

    2023年4月19日,據(jù)歐盟食品安全局(EFSA)消息,歐盟食品接觸材料、酶和加工助劑小組(CEP)重新評估雙酚A(BPA)對公眾健康的風(fēng)險(xiǎn)。

經(jīng)過評估,小組得出結(jié)論,膳食中暴露于BPA存在健康問題。部分原文報(bào)道如下:

In 2015, EFSA established a temporary tolerable daily intake (t-TDI) for BPA of 4 μg/kg body weight (bw) per day. In 2016, the European Commission mandated EFSA to re-evaluate the risks to public health from the presence of BPA in foodstuffs and to establish a tolerable daily intake (TDI). For this re-evaluation, a pre-established protocol was used that had undergone public consultation. The CEP Panel concluded that it is Unlikely to Very Unlikely that BPA presents a genotoxic hazard through a direct mechanism. Taking into consideration the evidence from animal data and support from human observational studies, the immune system was identified as most sensitive to BPA exposure. An effect on Th17 cells in mice was identified as the critical effect; these cells are pivotal in cellular immune mechanisms and involved in the development of inflammatory conditions, including autoimmunity and lung inflammation. A reference point (RP) of 8.2 ng/kg bw per day, expressed as human equivalent dose, was identified for the critical effect. Uncertainty analysis assessed a probability of 57–73% that the lowest estimated Benchmark Dose (BMD) for other health effects was below the RP based on Th17 cells. In view of this, the CEP Panel judged that an additional uncertainty factor (UF) of 2 was needed for establishing the TDI. Applying an overall UF of 50 to the RP, a TDI of 0.2 ng BPA/kg bw per day was established. Comparison of this TDI with the dietary exposure estimates from the 2015 EFSA opinion showed that both the mean and the 95th percentile dietary exposures in all age groups exceeded the TDI by two to three orders of magnitude. Even considering the uncertainty in the exposure assessment, the exceedance being so large, the CEP Panel concluded that there is a health concern from dietary BPA exposure.

編輯:qysb005

標(biāo)簽:

中國企業(yè)新聞網(wǎng)版權(quán)與免責(zé)聲明:
1、中國企業(yè)新聞網(wǎng)所有內(nèi)容的版權(quán)均屬于作者或頁面內(nèi)聲明的版權(quán)人。未經(jīng)中國企業(yè)新聞網(wǎng)的書面許可, 任何其他個(gè)人或組織均不得以任何形式將河南企業(yè)網(wǎng)的各項(xiàng)資源轉(zhuǎn)載、復(fù)制、編輯或發(fā)布使用于其他任何場合;不得把其中任何形式的資訊散發(fā)給其他方, 不可把這些信息在其他的服務(wù)器或文檔中作鏡像復(fù)制或保存;不得修改或再使用中國企業(yè)新聞網(wǎng)的任何資源。若有意轉(zhuǎn)載本站信息資料, 必需取得中國企業(yè)新聞網(wǎng)書面授權(quán)。否則將追究其法律責(zé)任。
2、已經(jīng)本網(wǎng)授權(quán)使用作品的,應(yīng)在授權(quán)范圍內(nèi)使用,并注明“來源:中國企業(yè)新聞網(wǎng)”。違反上述聲明者,本網(wǎng)將追究其相關(guān)法律責(zé)任。
3、凡本網(wǎng)注明“來源:XXX(非中國企業(yè)新聞網(wǎng))”的作品,均轉(zhuǎn)載自其它媒體,轉(zhuǎn)載目的在于傳遞更多信息, 并不代表本網(wǎng)贊同其觀點(diǎn)和對其真實(shí)性負(fù)責(zé)。本網(wǎng)轉(zhuǎn)載其他媒體之稿件,意在為公眾提供免費(fèi)服務(wù)。如稿件版權(quán)單位或個(gè)人不想在本網(wǎng)發(fā)布, 可與本網(wǎng)聯(lián)系,本網(wǎng)視情況可立即將其撤除。
圖片欣賞
頻道推薦
內(nèi)容推薦
最近更新