歐盟評(píng)估莫能霉素鈉作為育肥雞、產(chǎn)蛋雞和火雞飼料添加劑的安全性和有效性
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2023年6月9日,據(jù)歐盟食品安全局(EFSA)消息,應(yīng)歐盟委員會(huì)要求,歐盟動(dòng)物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就莫能霉素鈉(monensin sodium)作為育肥雞、產(chǎn)蛋雞和火雞飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。經(jīng)過評(píng)估,專家小組認(rèn)為在建議的使用條件下該添加劑對(duì)消費(fèi)者和環(huán)境是安全的,但不能對(duì)目標(biāo)物種的安全性得出結(jié)論。該添加劑在100mg/kg飼料水平下對(duì)16周齡以下的火雞是安全的,并且在60mg/kg全價(jià)飼料的最低濃度下具有控制球蟲病的潛力。部分原文報(bào)道如下:
Following a request from the European Commission, EFSA was asked to deliver a new scientific opinion on the coccidiostat monensin sodium (Elancoban?G200) when used as a feed additive for chickens for fattening and turkeys. based on the new data provided, the Panel updates its previous conclusions as follows: monensin sodium is produced by fermentation by a non-genetically modified strain of Streptomyces sp. NRRL B-67924. Genome analysis suggests the production strain may belong to a new species within the genus Streptomyces. The production strain and its DNA were not detected in the final additive. The product is free of antimicrobial activity other than monensin. The FEEDAP Panel cannot conclude on the safety of monensin sodium from Elancoban?G200 in feed for chickens for fattening and chickens reared for laying at the proposed maximum use level due to a dose-related reduction of the final body weight. The toxicological profile of monensin sodium was evaluated in studies made with the product obtained from the parental strain ATCC 15413. based on a comparison of the genomes of the two strains, the FEEDAP Panel concludes that toxicological equivalence has been established, thus the conclusions already drawn on Elancoban?G200 are valid for the product obtained with the new production strain concluding that the additive is safe for the consumer and the environment; the production strain does not represent an additional risk when safety for the user is considered. Monensin sodium from Elancoban?G200 is safe for turkeys up to 16 weeks of age at the concentration of 100 mg monensin sodium/kg feed and has the potential to control coccidiosis at the minimum concentration of 60 mg/kg complete feed.
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